Botanicula (PC, Mac) is a beautiful 2D handdrawn game with cute and weird characters, funny scenes and loads of adventures in a lush environment. The game's basic style is point and click with exploration with the occasional puzzle solving, but it's all done in a real artistic way, you feel like you're inside an indie animated feature while you are playing, check it out:
Tearaway (PS Vita) hasn't been released yet, though I've seen the first images and videos about it more than a year ago - and mind you, this is not a GTA style huge game, it's for a handheld console, so it should take a lot less time to produce it. The interesting thing for me in this game is not only the style, but the way you play it. The PS Vita has a touch-screen like surface at the bottom of it and utilizing that you can "reach" into the game and interact with the characters in completely new way. I don't have a PS Vita myself but this game itself looks promising enough to make me interested.